Updated:March, 2026

10 Best Vitamin B12 B6 And Folate Supplement of 2026

Best Choice

9.9

Outstanding

Superior Source

Superior Source No Shot Vitamin B-12 Methylcobalamin 1000 mcg, B-6 & Folic Acid 800 mcg - Supports Brain & Heart Health - Aids Natural Energy Levels - 60 Sublingual Dissolving Tablets

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Why We Love It

Vitamin Formulation: Each sublingual tablet contains 1000 mcg of B-12 Methylcobalamin, 800 mcg folic acid, and 2 mg B-6 for dietary supplementation
Energy Support: B vitamins, including B-12 and B-6, support cell production, brain health, and energy metabolism
Pure Ingredients: Our tablets are non-GMO, and contain no preservatives, focusing on providing a pure energy supplement
Enhanced Delivery: Superior Source's sublingual technology allows for rapid dissolution on or under the tongue, facilitating optimal absorption of B complex nutrients
About Us: Superior Source has been formulating sublingual vitamins since 1998 in our family-owned manufacturing facility

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Why We Love It

Vitamin Formulation: Each sublingual tablet contains 1000 mcg of B-12 Methylcobalamin, 800 mcg folic acid, and 2 mg B-6 for dietary supplementation
Energy Support: B vitamins, including B-12 and B-6, support cell production, brain health, and energy metabolism
Pure Ingredients: Our tablets are non-GMO, and contain no preservatives, focusing on providing a pure energy supplement
Enhanced Delivery: Superior Source's sublingual technology allows for rapid dissolution on or under the tongue, facilitating optimal absorption of B complex nutrients
About Us: Superior Source has been formulating sublingual vitamins since 1998 in our family-owned manufacturing facility

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9.5

Excellent

Vitamatic

Vitamatic Folic Acid, Vitamin B12 & B6 – 180 Fast Dissolve Tablets Heart Health, Energy Production & Red Blood Cell Support

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Main Highlights

Made with Folic Acid, Vitamin B12 & Vitamin B6
Heart Health, Energy & Red Blood Cell Support*
Non-GMO formula - Gluten Free
Free of sugar, starch, soy, yeast, corn, wheat, egg, artificial color, flavor & preservatives.
Made in the USA with Strict GMP standards.

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Main Highlights

Made with Folic Acid, Vitamin B12 & Vitamin B6
Heart Health, Energy & Red Blood Cell Support*
Non-GMO formula - Gluten Free
Free of sugar, starch, soy, yeast, corn, wheat, egg, artificial color, flavor & preservatives.
Made in the USA with Strict GMP standards.

9.5

Excellent

NUSAVA

(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Energy, Brain, and Heart Support with 27,200 mcg, Raspberry, 80 Servings

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Main Highlights

B12 Drops Formulated for Maximum Potency - Our Liquid Vitamin B12 Drops contain Vit B12 5000mcg, B6, B1, Niacin, and Folic Acid, supporting overall body functions with 100% or more Daily Value.
Tons of Benefits - Experience the synergy of brain support, digestive balance, energy metabolism, heart wellness, and immune support in each drop of our Vitamin B complex liquid sublingual formula.
Rapid Sublingual Absorption - Our Liquid B12 Drops are designed for efficient sublingual absorption. Just place the drops under your tongue for 30secs and swallow the remaining liquid. Quick and easy!
Carefully Curated Organic Vitamin B12 Liquid - Our Vitamin B12 Methylcobalamin B6 B1 Drops contain No Fillers, are Vegan, Non-GMO, Gluten-Free, and proudly USA-made with Global Ingredients.
Ultimate 5-in-1 Vitamin B12 Complex - Not all liquid supplements are made equal. Our B-12 Vitamin drops are packed with nutritional benefits. Each has 27,200 mcg. If youre unhappy with your purchase, do reach out to us.

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Main Highlights

B12 Drops Formulated for Maximum Potency - Our Liquid Vitamin B12 Drops contain Vit B12 5000mcg, B6, B1, Niacin, and Folic Acid, supporting overall body functions with 100% or more Daily Value.
Tons of Benefits - Experience the synergy of brain support, digestive balance, energy metabolism, heart wellness, and immune support in each drop of our Vitamin B complex liquid sublingual formula.
Rapid Sublingual Absorption - Our Liquid B12 Drops are designed for efficient sublingual absorption. Just place the drops under your tongue for 30secs and swallow the remaining liquid. Quick and easy!
Carefully Curated Organic Vitamin B12 Liquid - Our Vitamin B12 Methylcobalamin B6 B1 Drops contain No Fillers, are Vegan, Non-GMO, Gluten-Free, and proudly USA-made with Global Ingredients.
Ultimate 5-in-1 Vitamin B12 Complex - Not all liquid supplements are made equal. Our B-12 Vitamin drops are packed with nutritional benefits. Each has 27,200 mcg. If youre unhappy with your purchase, do reach out to us.

9.2

Excellent

NUSAVA

(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Energy, Brain, and Heart Support with 27,200 mcg, Fruit Punch, 80 Servings

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Main Highlights

B12 Drops Formulated for Maximum Potency - Our Liquid Vitamin B12 Drops contain Vit B12 5000mcg, B6, B1, Niacin, and Folic Acid, supporting overall body functions with 100% or more Daily Value.
Tons of Benefits - Experience the synergy of brain support, digestive balance, energy metabolism, heart wellness, and immune support in each drop of our Vitamin B complex liquid sublingual formula.
Rapid Sublingual Absorption - Our Liquid B12 Drops are designed for efficient sublingual absorption. Just place the drops under your tongue for 30secs and swallow the remaining liquid. Quick and easy!
Carefully Curated Organic Vitamin B12 Liquid - Our Vitamin B12 Methylcobalamin B6 B1 Drops contain No Fillers, are Vegan, Non-GMO, Gluten-Free, and proudly USA-made with Global Ingredients.
Ultimate 5-in-1 Vitamin B12 Complex - Not all liquid supplements are made equal. Our B-12 Vitamin drops are packed with nutritional benefits. If youre unhappy with your purchase, do reach out to us.

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Main Highlights

B12 Drops Formulated for Maximum Potency - Our Liquid Vitamin B12 Drops contain Vit B12 5000mcg, B6, B1, Niacin, and Folic Acid, supporting overall body functions with 100% or more Daily Value.
Tons of Benefits - Experience the synergy of brain support, digestive balance, energy metabolism, heart wellness, and immune support in each drop of our Vitamin B complex liquid sublingual formula.
Rapid Sublingual Absorption - Our Liquid B12 Drops are designed for efficient sublingual absorption. Just place the drops under your tongue for 30secs and swallow the remaining liquid. Quick and easy!
Carefully Curated Organic Vitamin B12 Liquid - Our Vitamin B12 Methylcobalamin B6 B1 Drops contain No Fillers, are Vegan, Non-GMO, Gluten-Free, and proudly USA-made with Global Ingredients.
Ultimate 5-in-1 Vitamin B12 Complex - Not all liquid supplements are made equal. Our B-12 Vitamin drops are packed with nutritional benefits. If youre unhappy with your purchase, do reach out to us.

9.0

Excellent

Vigorintha

Vigorintha Methylated Vitamin B6, B12 & Folate Gummies, Vitamin B6 Supplement with Methylated B12& L-Methylfolate for Energy, Brain & Nerve, Sugar Free, Vegan, 60 Gummies.

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Main Highlights

Advanced Methylated Formula for Better Absorption-Our folate and b12 supplement gummies feature the active methylated forms, P5P (B6), Methylcobalamin (B12), and L-Methylfolate for superior bioavailability. These forms are easier for your body to absorb and utilize, supporting energy and mood balance more effectively than synthetic vitamins.
Boost Energy & Brain Function Naturally-Packed with essential B6, B12 and folic acid vitamins, these methylfolate supplement gummies help convert food into fuel, promoting natural energy production, sharper focus, and better cognitive performance ideal for busy professionals and students alike.
Advanced Liquid-Filled Technology-Our Vitamin B6, B12 gummy is crafted with advanced liquid-filled core technology that locks inthe active nutrients, protecting them from oxidation and degradation.This ensures each gummy delivers maximum freshness, stability and potency, and delivers a refreshing burst of natural Raspberry flavor.
Gentle on the Stomach, Sugar-Free & Vegan-Our pectin based Vitamin B6 gummies are vegan, sugar-free, and free from artificial colors or preservativesperfect for daily use without guilt or digestive discomfort.
Premium Quality You Can Trust-Crafted with organic ingredients, third-party tested, and manufactured in a cGMP-certified facility, our Vitamin B6 gummies ensure purity, safety, and consistency.

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Main Highlights

Advanced Methylated Formula for Better Absorption-Our folate and b12 supplement gummies feature the active methylated forms, P5P (B6), Methylcobalamin (B12), and L-Methylfolate for superior bioavailability. These forms are easier for your body to absorb and utilize, supporting energy and mood balance more effectively than synthetic vitamins.
Boost Energy & Brain Function Naturally-Packed with essential B6, B12 and folic acid vitamins, these methylfolate supplement gummies help convert food into fuel, promoting natural energy production, sharper focus, and better cognitive performance ideal for busy professionals and students alike.
Advanced Liquid-Filled Technology-Our Vitamin B6, B12 gummy is crafted with advanced liquid-filled core technology that locks inthe active nutrients, protecting them from oxidation and degradation.This ensures each gummy delivers maximum freshness, stability and potency, and delivers a refreshing burst of natural Raspberry flavor.
Gentle on the Stomach, Sugar-Free & Vegan-Our pectin based Vitamin B6 gummies are vegan, sugar-free, and free from artificial colors or preservativesperfect for daily use without guilt or digestive discomfort.
Premium Quality You Can Trust-Crafted with organic ingredients, third-party tested, and manufactured in a cGMP-certified facility, our Vitamin B6 gummies ensure purity, safety, and consistency.

8.8

Very Good

Jarrow Formulas

Jarrow Formulas Methyl B-12 & Methyl Folate, Bioactive Vitamin B9 & Vitamin B12 Supplement, Supports Cellular Energy Production, Healthy Brain Function & Metabolism, 100 Chewable Tablets, 100 Servings

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Main Highlights

Cellular Energy Metabolism and Cardiovascular support supplement: Contains one 100 count bottle of Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg Chewable Tablets for a 100-day supply.
Offers a unique combination of B Vitamins in easy-to-take, lemon-flavored chewable tablets to support cellular energy metabolism, neurotransmitter synthesis and cardiovascular health.
Dietary supplement with Methyl B12, Methyl Folate and Pyridoxal-5-Phosphate (P-5-P), the active forms of Vitamins B-12, B9 and B6.
Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

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Main Highlights

Cellular Energy Metabolism and Cardiovascular support supplement: Contains one 100 count bottle of Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg Chewable Tablets for a 100-day supply.
Offers a unique combination of B Vitamins in easy-to-take, lemon-flavored chewable tablets to support cellular energy metabolism, neurotransmitter synthesis and cardiovascular health.
Dietary supplement with Methyl B12, Methyl Folate and Pyridoxal-5-Phosphate (P-5-P), the active forms of Vitamins B-12, B9 and B6.
Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

8.6

Very Good

KAL

KAL Vitamin B-6 B-12 Methyl Folate ActivMelt, Vitamin B Supplement, Heart Health, Energy and Red Blood Cell Support with Methyl B12 and DFE Folic Acid, Natural Berry Flavor, 60 Servings, 60 Micro Tabs

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Main Highlights

Superior B Action Each fast-dissolving micro tablet provides 3mg Vitamin B6, 2500mcg Vitamin B-12 Methylcobalamin and 400mcg DFE Methyl Folate (235mcg Folic Acid).
Strong Synergy Powerful B Vitamin blend is formulated to help support healthy energy levels and metabolism, red blood cell synthesis and normal homocysteine levels in the blood for a healthy heart.
Preferred Forms This hardworking B Complex formula contains B6 and B12 vitamins in their biologically active, coenzyme forms P-5-P B6 and Methyl B12 as well as Folate as 5-htmf.
ActivMelt Technology: Our trademarked micro tablets are designed to dissolve instantly in the mouth for optimal absorption. Youll love the great, natural mixed berry flavor.
KAL Quality: Vegetarian and sweetened with Stevia, our ActivMelt tablets are lab verified using the strictest standard to ensure purity and potency.

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Main Highlights

Superior B Action Each fast-dissolving micro tablet provides 3mg Vitamin B6, 2500mcg Vitamin B-12 Methylcobalamin and 400mcg DFE Methyl Folate (235mcg Folic Acid).
Strong Synergy Powerful B Vitamin blend is formulated to help support healthy energy levels and metabolism, red blood cell synthesis and normal homocysteine levels in the blood for a healthy heart.
Preferred Forms This hardworking B Complex formula contains B6 and B12 vitamins in their biologically active, coenzyme forms P-5-P B6 and Methyl B12 as well as Folate as 5-htmf.
ActivMelt Technology: Our trademarked micro tablets are designed to dissolve instantly in the mouth for optimal absorption. Youll love the great, natural mixed berry flavor.
KAL Quality: Vegetarian and sweetened with Stevia, our ActivMelt tablets are lab verified using the strictest standard to ensure purity and potency.

8.3

Very Good

Pure Encapsulations

Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves, Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules

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Main Highlights

Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs

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Main Highlights

Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs

8.1

Very Good

KAL

KAL Vitamin B-6, B-12 & Folic Acid Supplement, Heart Health, Energy & Red Blood Cell Support*, with Vitamin B12 Methylcobalamin & Folate, Natural Berry Flavor, 60 Servings, 60 ActivMelt Micro Tablets

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Main Highlights

Vitamin B Complex Blend - Our B complex formula delivers three powerful B vitamins to support cellular energy metabolism, nerve function, and overall wellness. Vitamin B12 (as methylcobalamin) and B6 are also key factors in red blood cell production and healthy homocysteine levels in the blood.*
No Water Required - Perfect for people who don't love swallowing pills, our quick-dissolving mixed-berry ActivMelts are convenient, taste great, and get right to work. Plus they're sweetened with stevia and naturally flavored.
Smart Choice Were proud to use 100% post-consumer resin (PCR) bottles made from plastic removed from oceans and landfills for a positive environmental impact.
KAL Quality Made in our GMP-certified facility and tested in our own state-of-the-art lab in Utah for the quality you deserve, our Vitamin B6 B12 Folic Acid always comes with a 60-Day Money Back Guarantee.

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Main Highlights

Vitamin B Complex Blend - Our B complex formula delivers three powerful B vitamins to support cellular energy metabolism, nerve function, and overall wellness. Vitamin B12 (as methylcobalamin) and B6 are also key factors in red blood cell production and healthy homocysteine levels in the blood.*
No Water Required - Perfect for people who don't love swallowing pills, our quick-dissolving mixed-berry ActivMelts are convenient, taste great, and get right to work. Plus they're sweetened with stevia and naturally flavored.
Smart Choice Were proud to use 100% post-consumer resin (PCR) bottles made from plastic removed from oceans and landfills for a positive environmental impact.
KAL Quality Made in our GMP-certified facility and tested in our own state-of-the-art lab in Utah for the quality you deserve, our Vitamin B6 B12 Folic Acid always comes with a 60-Day Money Back Guarantee.

8.1

Very Good

MASON NATURAL

MASON NATURAL Folic Acid with B,6 & B,12, 90 Day Supply, Supports Normal Heart Health and Metabolic Function

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Main Highlights

DAILY CARDIOVASCULAR SUPPORT: An easy-to-swallow tablet that adults 18+ take 1 daily, preferably with food, as a dietary supplement for healthy heart function
VITAMIN B6 & FOLATE: 50mg Vitamin B, 667mcg DFE Folate (400 mcg folic acid), 100mcg Vitamin B12, 44mg Calcium
BENEFITS: Known to support normal heart function
CLEAN INGREDIENTS: No added sugar, starch, yeast, soy, corn, wheat, gluten, fish, tree nuts, peanuts, egg, artificial colors or flavors, preservatives, animal products, crustacean shellfish and is sodium free
TRUSTED FOR OVER 50 YEARS: Mason Natural has produced quality vitamin supplements for over five decades, adhering to cGMPs (current Good Manufacturing Practices) and US guidelines with rigorous testing & inspections

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Main Highlights

DAILY CARDIOVASCULAR SUPPORT: An easy-to-swallow tablet that adults 18+ take 1 daily, preferably with food, as a dietary supplement for healthy heart function
VITAMIN B6 & FOLATE: 50mg Vitamin B, 667mcg DFE Folate (400 mcg folic acid), 100mcg Vitamin B12, 44mg Calcium
BENEFITS: Known to support normal heart function
CLEAN INGREDIENTS: No added sugar, starch, yeast, soy, corn, wheat, gluten, fish, tree nuts, peanuts, egg, artificial colors or flavors, preservatives, animal products, crustacean shellfish and is sodium free
TRUSTED FOR OVER 50 YEARS: Mason Natural has produced quality vitamin supplements for over five decades, adhering to cGMPs (current Good Manufacturing Practices) and US guidelines with rigorous testing & inspections

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